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Supporting innovative general practice research: The STAREE trial (EPOSTER: 4mins)

Presentation Description

Background: STAREE will provide general practitioners with a research-based educational programme that will enhance practitioners knowledge on evidence-based research techniques, utilising their own patient cohorts. STAREE is a general practice based NHMRC trial with no commercial sponsor. Its aim is to examine the benefits of statin therapy versus risks in healthy older people, determining whether atorvastatin maintains or improves quality of life in elderly patients. Outcomes may guide prescribing policies. https://www.monash.edu/medicine/staree/home 
 
Method: STAREE is a statin-placebo controlled, double-blind, randomised trial enrolling men and women 70 years and over, comparing Atorvastatin 40mg vs placebo, aiming to recruit 10,000 nationally. Exclusions are existing cardiovascular disease, diabetes, dementia, plus participants need to live independently in the community Co-Primary Endpoints: Time to death, or development of dementia or disability Time to major fatal or non-fatal cardiovascular events Secondary endpoints Cardiovascular death, Myocardial infarction, Stroke, Approved need for Residential Care, Unplanned All-cause Hospitalisation, New onset Diabetes, Cancer fatal and non-fatal, All-cause Dementia, Quality of Life, Cost - effectiveness of Statin, Frailty / Disability, and Cognitive Decline. 
 
Results: Recruitment still occurring nationally 
 
Discussion: Communication is supported by GP educational newsletters. Recruitment will utilise existing GP practice recall processes, via computerised databases, supervised and supported at each practice site by the research team, with administrative support of $100 per randomised participant. Average follow-up is 5 years with 6th monthly research staff visits. 
 
Implications for practice: Facilitate each GPs involvement and research knowledge acquisition, supported by a accompanying RACGP CPD audit programme. Develop, and maintain a national network of general practices by integrating research within existing practice systems

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